Randomized, Prospective Evaluation Comparing Intensity of Lymphodepletion Before Adoptive Transfer of Tumor-Infiltrating Lymphocytes for Patients With Metastatic Melanoma

PURPOSE: Adoptive cell transfer, the infusion of large numbers of activated autologous lymphocytes, can mediate objective tumor regression in a majority of patients with metastatic melanoma (52 of 93; 56%). Addition and intensification of total body irradiation (TBI) to the preparative lymphodepleti...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Clin Oncol
Hauptverfasser: Goff, Stephanie L., Dudley, Mark E., Citrin, Deborah E., Somerville, Robert P., Wunderlich, John R., Danforth, David N., Zlott, Daniel A., Yang, James C., Sherry, Richard M., Kammula, Udai S., Klebanoff, Christopher A., Hughes, Marybeth S., Restifo, Nicholas P., Langhan, Michelle M., Shelton, Thomas E., Lu, Lily, Kwong, Mei Li M., Ilyas, Sadia, Klemen, Nicholas D., Payabyab, Eden C., Morton, Kathleen E., Toomey, Mary Ann, Steinberg, Seth M., White, Donald E., Rosenberg, Steven A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Clinical Oncology 2016
Schlagworte:
Original Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981979/
https://ncbi.nlm.nih.gov/pubmed/27217459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2016.66.7220
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge