Randomized, Prospective Evaluation Comparing Intensity of Lymphodepletion Before Adoptive Transfer of Tumor-Infiltrating Lymphocytes for Patients With Metastatic Melanoma

PURPOSE: Adoptive cell transfer, the infusion of large numbers of activated autologous lymphocytes, can mediate objective tumor regression in a majority of patients with metastatic melanoma (52 of 93; 56%). Addition and intensification of total body irradiation (TBI) to the preparative lymphodepleti...

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Bibliografski detalji
Izdano u:J Clin Oncol
Glavni autori: Goff, Stephanie L., Dudley, Mark E., Citrin, Deborah E., Somerville, Robert P., Wunderlich, John R., Danforth, David N., Zlott, Daniel A., Yang, James C., Sherry, Richard M., Kammula, Udai S., Klebanoff, Christopher A., Hughes, Marybeth S., Restifo, Nicholas P., Langhan, Michelle M., Shelton, Thomas E., Lu, Lily, Kwong, Mei Li M., Ilyas, Sadia, Klemen, Nicholas D., Payabyab, Eden C., Morton, Kathleen E., Toomey, Mary Ann, Steinberg, Seth M., White, Donald E., Rosenberg, Steven A.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Clinical Oncology 2016
Teme:
Original Reports
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981979/
https://ncbi.nlm.nih.gov/pubmed/27217459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2016.66.7220
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