Adoptive Cell Transfer Therapy Following Non-Myeloablative but Lymphodepleting Chemotherapy for the Treatment of Patients With Refractory Metastatic Melanoma

Purpose We investigated the combination of lymphodepleting chemotherapy followed by the adoptive transfer of autologous tumor reactive lymphocytes for the treatment of patients with refractory metastatic melanoma. Patients and Methods Thirty-five patients with metastatic melanoma, all but one with d...

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Main Authors: Dudley, Mark E., Wunderlich, John R., Yang, James C., Sherry, Richard M., Topalian, Suzanne L., Restifo, Nicholas P., Royal, Richard E., Kammula, Udai, White, Don E., Mavroukakis, Sharon A., Rogers, Linda J., Gracia, Gerald J., Jones, Stephanie A., Mangiameli, David P., Pelletier, Michelle M., Gea-Banacloche, Juan, Robinson, Michael R., Berman, David M., Filie, Armando C., Abati, Andrea, Rosenberg, Steven A.
Format: Artigo
Sprog:Inglês
Udgivet: 2005
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1475951/
https://ncbi.nlm.nih.gov/pubmed/15800326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2005.00.240
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