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The transcription factor ATF5 mediates a mammalian mitochondrial UPR

Mitochondrial dysfunction is pervasive in human pathologies such as neurodegeneration, diabetes, cancer and pathogen infections as well as during normal aging. Cells sense and respond to mitochondrial dysfunction by activating a protective transcriptional program known as the mitochondrial unfolded...

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Bibliografski detalji
Izdano u:Curr Biol
Glavni autori: Fiorese, Christopher J., Schulz, Anna M., Lin, Yi-Fan, Rosin, Nadine, Pellegrino, Mark W., Haynes, Cole M.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980197/
https://ncbi.nlm.nih.gov/pubmed/27426517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2016.06.002
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