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The transcription factor ATF5 mediates a mammalian mitochondrial UPR
Mitochondrial dysfunction is pervasive in human pathologies such as neurodegeneration, diabetes, cancer and pathogen infections as well as during normal aging. Cells sense and respond to mitochondrial dysfunction by activating a protective transcriptional program known as the mitochondrial unfolded...
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| Yayımlandı: | Curr Biol |
|---|---|
| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4980197/ https://ncbi.nlm.nih.gov/pubmed/27426517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2016.06.002 |
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