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Mitochondrial and nuclear accumulation of the transcription factor ATFS-1 promotes OXPHOS recovery during the UPR(mt)

Mitochondrial diseases and aging are associated with defects in the oxidative phosphorylation machinery (OXPHOS), which are the only complexes composed of proteins encoded by separate genomes. To better understand genome coordination and OXPHOS recovery during mitochondrial dysfunction, we examined...

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Pubblicato in:Mol Cell
Autori principali: Nargund, Amrita M., Fiorese, Christopher J., Pellegrino, Mark W., Deng, Pan, Haynes, Cole M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385436/
https://ncbi.nlm.nih.gov/pubmed/25773600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.02.008
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