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The transcription factor ATF5 mediates a mammalian mitochondrial UPR
Mitochondrial dysfunction is pervasive in human pathologies such as neurodegeneration, diabetes, cancer and pathogen infections as well as during normal aging. Cells sense and respond to mitochondrial dysfunction by activating a protective transcriptional program known as the mitochondrial unfolded...
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| Publicado no: | Curr Biol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4980197/ https://ncbi.nlm.nih.gov/pubmed/27426517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2016.06.002 |
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