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Evaluating and responding to mitochondrial dysfunction: The UPR(mt) and beyond

During development and cellular differentiation, tissue and cell-specific programs mediate mitochondrial biogenesis in order to meet physiological needs. However, environmental and disease-associated factors can perturb mitochondrial activities requiring cells to adapt to protect mitochondria and ma...

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Bibliographic Details
Main Authors: Haynes, Cole M., Fiorese, Christopher J., Lin, Yi-Fan
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700555/
https://ncbi.nlm.nih.gov/pubmed/23489877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2013.02.002
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