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Mitochondrial Import Efficiency of ATFS-1 Regulates Mitochondrial UPR Activation

To better understand the response to mitochondrial dysfunction, we examined the mechanism by which Activating Transcription Factor associated with Stress-1 (ATFS-1) senses mitochondrial stress and communicates with the nucleus during the mitochondrial unfolded protein response (UPR(mt)). We found th...

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Detalhes bibliográficos
Main Authors: Nargund, Amrita M., Pellegrino, Mark W., Fiorese, Christopher J., Baker, Brooke M., Haynes, Cole M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518298/
https://ncbi.nlm.nih.gov/pubmed/22700657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1223560
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