Cutoff suppresses RNA polymerase II termination to ensure expression of piRNA precursors

Small non-coding RNAs called piRNAs serve as guides for an adaptable immune system that represses transposable elements in germ cells of Metazoa. In Drosophila the RDC complex, composed of Rhino, Deadlock and Cutoff (Cuff) binds chromatin of dual-strand piRNA clusters, special genomic regions, which...

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書誌詳細
出版年:Mol Cell
主要な著者: Chen, Yung-Chia Ariel, Stuwe, Evelyn, Luo, Yicheng, Ninova, Maria, Le Thomas, Adrien, Rozhavskaya, Ekaterina, Li, Sisi, Vempati, Sivani, Laver, John D., Patel, Dinshaw J., Smibert, Craig A., Lipshitz, Howard D., Toth, Katalin Fejes, Aravin, Alexei A.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980073/
https://ncbi.nlm.nih.gov/pubmed/27292797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.05.010
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