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To be or not to be a piRNA: genomic origin and processing of piRNAs

Piwi-interacting RNAs (piRNAs) originate from genomic regions dubbed piRNA clusters. How cluster transcripts are selected for processing into piRNAs is not understood. We discuss evidence for the involvement of chromatin structure and maternally inherited piRNAs in determining their fate.

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Le Thomas, Adrien, Tóth, Katalin Fejes, Aravin, Alexei A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053809/
https://ncbi.nlm.nih.gov/pubmed/24467990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb4154
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