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mTORC2 controls cancer cell survival by modulating gluconeogenesis

For rapid tumor growth, cancer cells often reprogram the cellular metabolic processes to obtain enhanced anabolic precursors and energy. The molecular changes of such metabolic rewiring are far from established. Here we explored the role of mTOR (mechanistic target of rapamycin), which serves as a k...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell Death Discov
Asıl Yazarlar: Khan, MW, Biswas, D, Ghosh, M, Mandloi, S, Chakrabarti, S, Chakrabarti, P
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979518/
https://ncbi.nlm.nih.gov/pubmed/27551450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2015.16
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