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mTORC2 controls cancer cell survival by modulating gluconeogenesis

For rapid tumor growth, cancer cells often reprogram the cellular metabolic processes to obtain enhanced anabolic precursors and energy. The molecular changes of such metabolic rewiring are far from established. Here we explored the role of mTOR (mechanistic target of rapamycin), which serves as a k...

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Detalhes bibliográficos
Publicado no:Cell Death Discov
Main Authors: Khan, MW, Biswas, D, Ghosh, M, Mandloi, S, Chakrabarti, S, Chakrabarti, P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979518/
https://ncbi.nlm.nih.gov/pubmed/27551450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2015.16
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