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mTORC2 controls cancer cell survival by modulating gluconeogenesis

For rapid tumor growth, cancer cells often reprogram the cellular metabolic processes to obtain enhanced anabolic precursors and energy. The molecular changes of such metabolic rewiring are far from established. Here we explored the role of mTOR (mechanistic target of rapamycin), which serves as a k...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Discov
Hauptverfasser: Khan, MW, Biswas, D, Ghosh, M, Mandloi, S, Chakrabarti, S, Chakrabarti, P
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979518/
https://ncbi.nlm.nih.gov/pubmed/27551450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2015.16
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