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mTORC2 controls cancer cell survival by modulating gluconeogenesis

For rapid tumor growth, cancer cells often reprogram the cellular metabolic processes to obtain enhanced anabolic precursors and energy. The molecular changes of such metabolic rewiring are far from established. Here we explored the role of mTOR (mechanistic target of rapamycin), which serves as a k...

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Podrobná bibliografie
Vydáno v:Cell Death Discov
Hlavní autoři: Khan, MW, Biswas, D, Ghosh, M, Mandloi, S, Chakrabarti, S, Chakrabarti, P
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979518/
https://ncbi.nlm.nih.gov/pubmed/27551450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2015.16
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