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C3 exoenzyme impairs cell proliferation and apoptosis by altering the activity of transcription factors

C3 exoenzyme from C. botulinum is an ADP-ribosyltransferase that inactivates selectively RhoA, B, and C by coupling an ADP-ribose moiety. Rho-GTPases are involved in various cellular processes, such as regulation of actin cytoskeleton, cell proliferation, and apoptosis. Previous studies of our group...

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Detaylı Bibliyografya
Yayımlandı:Naunyn Schmiedebergs Arch Pharmacol
Asıl Yazarlar: von Elsner, Leonie, Hagemann, Sandra, Just, Ingo, Rohrbeck, Astrid
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer Berlin Heidelberg 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4977334/
https://ncbi.nlm.nih.gov/pubmed/27351882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-016-1270-2
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