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Anti-proliferative Effect of C3 Exoenzyme in Fibroblasts is Mediated by c-Jun Phosphorylation

The ADP-ribosyltransferase C3 exoenzyme from C. botulinum selectively inactivates Rho and is therefore often used as an inhibitor for investigations on Rho signaling. Previous studies of our group revealed that C3 inhibited cell proliferation in HT22 cells accompanied by increased transcriptional ac...

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Bibliographic Details
Published in:J Mol Signal
Main Authors: von Elsner, Leonie, Hagemann, Sandra, Just, Ingo, Rohrbeck, Astrid
Format: Artigo
Language:Inglês
Published: Ubiquity Press 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630077/
https://ncbi.nlm.nih.gov/pubmed/30210577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5334/1750-2187-12-1
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