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Vimentin Mediates Uptake of C3 Exoenzyme

Clostridium botulinum C3 exoenzyme (C3) selectively inactivates RhoA/B/C GTPases by ADP-ribosylation. Based on this substrate specificity C3 is a well-established tool in cell biology. C3 is taken up by eukaryotic cells although lacking an uptake and translocation domain. Based on different approach...

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Autors principals: Rohrbeck, Astrid, Schröder, Anke, Hagemann, Sandra, Pich, Andreas, Höltje, Markus, Ahnert-Hilger, Gudrun, Just, Ingo
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072758/
https://ncbi.nlm.nih.gov/pubmed/24967582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101071
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