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Uptake of Clostridium botulinum C3 Exoenzyme into Intact HT22 and J774A.1 Cells
The Clostridium botulinum C3 exoenzyme selectively ADP-ribosylates low molecular weight GTP-binding proteins RhoA, B and C. This covalent modification inhibits Rho signaling activity, resulting in distinct actin cytoskeleton changes. Although C3 exoenzyme has no binding, the translocation domain ass...
Salvato in:
| Pubblicato in: | Toxins (Basel) |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4344630/ https://ncbi.nlm.nih.gov/pubmed/25648844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins7020380 |
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