The Rho ADP-ribosylating C3 exoenzyme binds cells via an Arg–Gly–Asp motif

The Rho ADP-ribosylating C3 exoenzyme (C3bot) is a bacterial protein toxin devoid of a cell-binding or -translocation domain. Nevertheless, C3 can efficiently enter intact cells, including neurons, but the mechanism of C3 binding and uptake is not yet understood. Previously, we identified the interm...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Rohrbeck, Astrid, Höltje, Markus, Adolf, Andrej, Oms, Elisabeth, Hagemann, Sandra, Ahnert-Hilger, Gudrun, Just, Ingo
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2017
Sujets:
Cell Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663871/
https://ncbi.nlm.nih.gov/pubmed/28882889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.798231
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