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C3 exoenzyme impairs cell proliferation and apoptosis by altering the activity of transcription factors
C3 exoenzyme from C. botulinum is an ADP-ribosyltransferase that inactivates selectively RhoA, B, and C by coupling an ADP-ribose moiety. Rho-GTPases are involved in various cellular processes, such as regulation of actin cytoskeleton, cell proliferation, and apoptosis. Previous studies of our group...
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| Publicado no: | Naunyn Schmiedebergs Arch Pharmacol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4977334/ https://ncbi.nlm.nih.gov/pubmed/27351882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-016-1270-2 |
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