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Probing γ‐secretase–substrate interactions at the single amino acid residue level
Intramembrane proteolysis by γ‐secretases plays major roles in disease pathology and cellular signalling, yet the dynamics of these enzyme complexes and how they recognize substrates remains poorly understood. New work in The EMBO Journal utilizes photo‐affinity cross‐linking to map APP interactions...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4969572/ https://ncbi.nlm.nih.gov/pubmed/27370209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201694978 |
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