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The dynamic conformational landscape of γ-secretase
The structure and function of the γ-secretase proteases are of great interest because of their crucial roles in cellular and disease processes. We established a novel purification protocol for the γ-secretase complex that involves a conformation- and complex-specific nanobody, yielding highly pure a...
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| Publicado no: | J Cell Sci |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4311135/ https://ncbi.nlm.nih.gov/pubmed/25501811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.164384 |
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