Modification of γ-secretase by nitrosative stress links neuronal ageing to sporadic Alzheimer's disease

Inherited familial Alzheimer's disease (AD) is characterized by small increases in the ratio of Aβ42 versus Aβ40 peptide which is thought to drive the amyloid plaque formation in the brain of these patients. Little is known however whether ageing, the major risk factor for sporadic AD, affects...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Guix, Francesc X, Wahle, Tina, Vennekens, Kristel, Snellinx, An, Chávez-Gutiérrez, Lucía, Ill-Raga, Gerard, Ramos-Fernandez, Eva, Guardia-Laguarta, Cristina, Lleó, Alberto, Arimon, Muriel, Berezovska, Oksana, Muñoz, Francisco J, Dotti, Carlos G, De Strooper, Bart
Формат: Artigo
Язык:Inglês
Опубликовано: WILEY-VCH Verlag 2012
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402223/
https://ncbi.nlm.nih.gov/pubmed/22488900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201200243
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы