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Signature Amyloid β Profiles Are Produced by Different γ-Secretase Complexes
γ-Secretase complexes are involved in the generation of amyloid-β (Aβ) in the brain. Therefore, γ-secretase has been proposed as a potential therapeutic target in Alzheimer disease (AD). Targeting γ-secretase activity in AD requires the pharmacological dissociation of the processing of physiological...
Gorde:
| Egile Nagusiak: | , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society for Biochemistry and Molecular Biology
2014
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3924297/ https://ncbi.nlm.nih.gov/pubmed/24338474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.530907 |
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