Llwytho...

Probing γ‐secretase–substrate interactions at the single amino acid residue level

Intramembrane proteolysis by γ‐secretases plays major roles in disease pathology and cellular signalling, yet the dynamics of these enzyme complexes and how they recognize substrates remains poorly understood. New work in The EMBO Journal utilizes photo‐affinity cross‐linking to map APP interactions...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO J
Prif Awduron: Chávez‐Gutiérrez, Lucía, De Strooper, Bart
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969572/
https://ncbi.nlm.nih.gov/pubmed/27370209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201694978
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