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MicroRNA 433 regulates nonsense-mediated mRNA decay by targeting SMG5 mRNA
BACKGROUND: Nonsense-mediated mRNA decay (NMD) is a RNA quality surveillance system for eukaryotes. It prevents cells from generating deleterious truncated proteins by degrading abnormal mRNAs that harbor premature termination codon (PTC). However, little is known about the molecular regulation mech...
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| Izdano u: | BMC Mol Biol |
|---|---|
| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4966760/ https://ncbi.nlm.nih.gov/pubmed/27473591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12867-016-0070-z |
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