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MicroRNA 433 regulates nonsense-mediated mRNA decay by targeting SMG5 mRNA
BACKGROUND: Nonsense-mediated mRNA decay (NMD) is a RNA quality surveillance system for eukaryotes. It prevents cells from generating deleterious truncated proteins by degrading abnormal mRNAs that harbor premature termination codon (PTC). However, little is known about the molecular regulation mech...
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Publicado no: | BMC Mol Biol |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4966760/ https://ncbi.nlm.nih.gov/pubmed/27473591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12867-016-0070-z |
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