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MicroRNA 433 regulates nonsense-mediated mRNA decay by targeting SMG5 mRNA

BACKGROUND: Nonsense-mediated mRNA decay (NMD) is a RNA quality surveillance system for eukaryotes. It prevents cells from generating deleterious truncated proteins by degrading abnormal mRNAs that harbor premature termination codon (PTC). However, little is known about the molecular regulation mech...

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Detalhes bibliográficos
Publicado no:BMC Mol Biol
Main Authors: Jin, Yi, Zhang, Fang, Ma, Zhenfa, Ren, Zhuqing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966760/
https://ncbi.nlm.nih.gov/pubmed/27473591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12867-016-0070-z
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