MicroRNA 433 regulates nonsense-mediated mRNA decay by targeting SMG5 mRNA

BACKGROUND: Nonsense-mediated mRNA decay (NMD) is a RNA quality surveillance system for eukaryotes. It prevents cells from generating deleterious truncated proteins by degrading abnormal mRNAs that harbor premature termination codon (PTC). However, little is known about the molecular regulation mech...

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Bibliographic Details
Published in:BMC Mol Biol
Main Authors: Jin, Yi, Zhang, Fang, Ma, Zhenfa, Ren, Zhuqing
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966760/
https://ncbi.nlm.nih.gov/pubmed/27473591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12867-016-0070-z
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