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MicroRNA 433 regulates nonsense-mediated mRNA decay by targeting SMG5 mRNA
BACKGROUND: Nonsense-mediated mRNA decay (NMD) is a RNA quality surveillance system for eukaryotes. It prevents cells from generating deleterious truncated proteins by degrading abnormal mRNAs that harbor premature termination codon (PTC). However, little is known about the molecular regulation mech...
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| 出版年: | BMC Mol Biol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4966760/ https://ncbi.nlm.nih.gov/pubmed/27473591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12867-016-0070-z |
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