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MicroRNA 433 regulates nonsense-mediated mRNA decay by targeting SMG5 mRNA

BACKGROUND: Nonsense-mediated mRNA decay (NMD) is a RNA quality surveillance system for eukaryotes. It prevents cells from generating deleterious truncated proteins by degrading abnormal mRNAs that harbor premature termination codon (PTC). However, little is known about the molecular regulation mech...

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發表在:BMC Mol Biol
Main Authors: Jin, Yi, Zhang, Fang, Ma, Zhenfa, Ren, Zhuqing
格式: Artigo
語言:Inglês
出版: BioMed Central 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966760/
https://ncbi.nlm.nih.gov/pubmed/27473591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12867-016-0070-z
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