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Characterization of SMG-9, an essential component of the nonsense-mediated mRNA decay SMG1C complex
SMG-9 is part of a protein kinase complex, SMG1C, which consists of the SMG-1 kinase, SMG-8 and SMG-9. SMG1C mediated phosphorylation of Upf1 triggers nonsense-mediated mRNA decay (NMD), a eukaryotic surveillance pathway that detects and targets for degradation mRNAs harboring premature translation...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3017601/ https://ncbi.nlm.nih.gov/pubmed/20817927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq749 |
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