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Mutant p53 regulates ovarian cancer transformed phenotypes through autocrine matrix deposition
High-grade serous ovarian carcinoma (HGS-OvCa) harbors p53 mutations and can originate from the epithelial cell compartment of the fallopian tube fimbriae. From this site, neoplastic cells detach, survive in the peritoneal cavity, and form cellular clusters that intercalate into the mesothelium to f...
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| Publicado no: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4963159/ https://ncbi.nlm.nih.gov/pubmed/27482544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.86829 |
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