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p53 suppresses hyper-recombination by modulating BRCA1 function
Both p53 and BRCA1 are tumor suppressors and are involved in a number of cellular processes including cell cycle arrest, apoptosis, transcriptional regulation, and DNA damage repair. Some studies have suggested that the association of BRCA1 and p53 is required for transcriptional regulation of genes...
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| Udgivet i: | DNA Repair (Amst) |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4960982/ https://ncbi.nlm.nih.gov/pubmed/26162908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2015.06.005 |
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