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p53 suppresses hyper-recombination by modulating BRCA1 function

Both p53 and BRCA1 are tumor suppressors and are involved in a number of cellular processes including cell cycle arrest, apoptosis, transcriptional regulation, and DNA damage repair. Some studies have suggested that the association of BRCA1 and p53 is required for transcriptional regulation of genes...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:DNA Repair (Amst)
Asıl Yazarlar: Dong, Chao, Zhang, Fengmei, Luo, Yue, Wang, Hui, Zhao, Xipeng, Guo, Gongshe, Powell, Simon N., Feng, Zhihui
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960982/
https://ncbi.nlm.nih.gov/pubmed/26162908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2015.06.005
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