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Valproic acid causes radiosensitivity of breast cancer cells via disrupting the DNA repair pathway

Valproic acid (VPA) is one of the representative compounds of histone deacetylase inhibitors (HDACis) and is used widely for the clinical treatment of epilepsy and other convulsive diseases. Current reports indicate that HDACis may also be an attractive radiosensitizer for some tumor cells; however,...

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Podrobná bibliografie
Vydáno v:Toxicol Res (Camb)
Hlavní autoři: Luo, Yue, Wang, Hui, Zhao, Xipeng, Dong, Chao, Zhang, Fengmei, Guo, Gang, Guo, Gongshe, Wang, Xiaowei, Powell, Simon N., Feng, Zhihui
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060714/
https://ncbi.nlm.nih.gov/pubmed/30090395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5tx00476d
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