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Valproic acid causes radiosensitivity of breast cancer cells via disrupting the DNA repair pathway

Valproic acid (VPA) is one of the representative compounds of histone deacetylase inhibitors (HDACis) and is used widely for the clinical treatment of epilepsy and other convulsive diseases. Current reports indicate that HDACis may also be an attractive radiosensitizer for some tumor cells; however,...

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Detalhes bibliográficos
Publicado no:Toxicol Res (Camb)
Principais autores: Luo, Yue, Wang, Hui, Zhao, Xipeng, Dong, Chao, Zhang, Fengmei, Guo, Gang, Guo, Gongshe, Wang, Xiaowei, Powell, Simon N., Feng, Zhihui
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060714/
https://ncbi.nlm.nih.gov/pubmed/30090395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5tx00476d
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