The Valproate Mediates Radio-Bidirectional Regulation Through RFWD3-Dependent Ubiquitination on Rad51

Ionizing radiation (IR) can induce DNA double-strand breaks (DSBs) in tumor cells during radiotherapy (RT), but the efficiency of RT is limited because of the toxicity to normal cells. Locating an adjuvant treatment to alleviate damage in normal cells while sensitizing tumor cells to IR has attracte...

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Dades bibliogràfiques
Publicat a:Front Oncol
Autors principals: Liu, Guochao, Lim, David, Cai, Zuchao, Ding, Wenwen, Tian, Zhujun, Dong, Chao, Zhang, Fengmei, Guo, Gongshe, Wang, Xiaowei, Zhou, Pingkun, Feng, Zhihui
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Oncology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029989/
https://ncbi.nlm.nih.gov/pubmed/33842359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.646256
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