The Valproate Mediates Radio-Bidirectional Regulation Through RFWD3-Dependent Ubiquitination on Rad51

Ionizing radiation (IR) can induce DNA double-strand breaks (DSBs) in tumor cells during radiotherapy (RT), but the efficiency of RT is limited because of the toxicity to normal cells. Locating an adjuvant treatment to alleviate damage in normal cells while sensitizing tumor cells to IR has attracte...

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Udgivet i:Front Oncol
Main Authors: Liu, Guochao, Lim, David, Cai, Zuchao, Ding, Wenwen, Tian, Zhujun, Dong, Chao, Zhang, Fengmei, Guo, Gongshe, Wang, Xiaowei, Zhou, Pingkun, Feng, Zhihui
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029989/
https://ncbi.nlm.nih.gov/pubmed/33842359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.646256
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