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A dual role of BRCA1 in two distinct homologous recombination mediated repair in response to replication arrest
Homologous recombination (HR) is a major mechanism utilized to repair blockage of DNA replication forks. Here, we report that a sister chromatid exchange (SCE) generated by crossover-associated HR efficiently occurs in response to replication fork stalling before any measurable DNA double-strand bre...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3258139/ https://ncbi.nlm.nih.gov/pubmed/21954437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr748 |
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