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The role of BRCA1 in homologous recombination repair in response to replication stress: significance in tumorigenesis and cancer therapy
Germ line mutations in breast cancer gene 1 (BRCA1) predispose women to breast and ovarian cancers. Although BRCA1 is involved in many important biological processes, the function of BRCA1 in homologous recombination (HR) mediated repair is considered one of the major mechanisms contributing to its...
Tallennettuna:
| Päätekijä: | |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
BioMed Central
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3599463/ https://ncbi.nlm.nih.gov/pubmed/23388117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3701-3-11 |
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