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Altered Type II Interferon Precedes Autoantibody Accrual and Elevated Type I Interferon Activity Prior to Systemic Lupus Erythematosus Classification

OBJECTIVES: The relationship of immune dysregulation and autoantibody production that may contribute to systemic lupus erythematosus (SLE) pathogenesis is unknown. This study evaluates the individual and combined contributions of autoantibodies, type I interferon (IFN-α) activity, and IFN-associated...

詳細記述

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書誌詳細
出版年:Ann Rheum Dis
主要な著者: Munroe, Melissa E., Lu, Rufei, Zhao, Yan D., Fife, Dustin A., Robertson, Julie M., Guthridge, Joel M., Niewold, Timothy B., Tsokos, George C., Keith, Michael P., Harley, John B., James, Judith A.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959992/
https://ncbi.nlm.nih.gov/pubmed/27088255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2015-208140
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