Dysregulation of Innate and Adaptive Serum Mediators Precedes Systemic Lupus Erythematosus Classification and Improves Prognostic Accuracy of Autoantibodies

Systemic lupus erythematosus (SLE) is a complex autoimmune disease with a poorly understood preclinical stage of immune dysregulation and symptom accrual. Accumulation of antinuclear autoantibody (ANA) specificities is a hallmark of impending clinical disease. Yet, many ANA-positive individuals rema...

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Publicado no:J Autoimmun
Main Authors: Lu, Rufei, Munroe, Melissa E., Guthridge, Joel M., Bean, Krista M., Fife, Dustin A., Chen, Hua, Slight-Webb, Samantha R., Keith, Michael P., Harley, John B., James, Judith A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079766/
https://ncbi.nlm.nih.gov/pubmed/27338520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2016.06.001
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