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Type I interferon in the pathogenesis of systemic lupus erythematosus
Type I interferon (IFN) is a primary pathogenic factor in systemic lupus erythematosus (SLE). Gain-of-function genetic variants in the type I IFN pathway have been associated with risk of disease. Common polygenic as well as rare monogenic influences on type I IFN have been demonstrated, supporting...
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| Publicado en: | Curr Opin Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8054829/ https://ncbi.nlm.nih.gov/pubmed/33246136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2020.10.014 |
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