Dysregulation of antiviral helicase pathways in systemic lupus erythematosus

In the autoimmune disease systemic lupus erythematosus (SLE), our normal antiviral defenses are inappropriately activated, resulting in over-activity of the type I interferon (IFN) pathway. This increased activity of the type I IFN pathway is an important primary pathogenic factor in the disease. Em...

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Udgivet i:Front Genet
Main Authors: Oliveira, Luciana, Sinicato, Nailú A., Postal, Mariana, Appenzeller, Simone, Niewold, Timothy B.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2014
Fag:
Genetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243696/
https://ncbi.nlm.nih.gov/pubmed/25505487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00418
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