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Nucleic Acid Sensors and Type I Interferon Production in Systemic Lupus Erythematosus

The characteristic serologic feature of systemic lupus erythematosus (SLE) is autoantibodies against one’s own nucleic acid or nucleic acid-binding proteins – DNA and RNA-binding nuclear proteins. Circulating autoantibodies can deposit in the tissue, causing inflammation and production of cytokines...

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Bibliografske podrobnosti
Main Authors: Shrivastav, Meena, Niewold, Timothy B.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791549/
https://ncbi.nlm.nih.gov/pubmed/24109483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00319
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