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Shutdown of HIV-1 Transcription in T Cells by Nullbasic, a Mutant Tat Protein
Nullbasic is a derivative of the HIV-1 transactivator of transcription (Tat) protein that strongly inhibits HIV-1 replication in lymphocytes. Here we show that lentiviral vectors that constitutively express a Nullbasic-ZsGreen1 (NB-ZSG1) fusion protein by the eEF1α promoter led to robust long-term i...
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| Publicado en: | mBio |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4958243/ https://ncbi.nlm.nih.gov/pubmed/27381288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00518-16 |
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