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Differential Effects of Strategies to Improve the Transduction Efficiency of Lentiviral Vector that Conveys an Anti-HIV Protein, Nullbasic, in Human T Cells

Nullbasic is a mutant form of HIV-1 Tat that has strong ability to protect cells from HIV-1 replication by inhibiting three different steps of viral replication: reverse transcription, Rev export of viral mRNA from the nucleus to the cytoplasm and transcription of viral mRNA by RNA polymerase II. We...

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Bibliografiska uppgifter
I publikationen:Virol Sin
Huvudupphovsmän: Rustanti, Lina, Jin, Hongping, Li, Dongsheng, Lor, Mary, Sivakumaran, Haran, Harrich, David
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer Singapore 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6178113/
https://ncbi.nlm.nih.gov/pubmed/29541943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12250-018-0004-7
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