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Differential Effects of Strategies to Improve the Transduction Efficiency of Lentiviral Vector that Conveys an Anti-HIV Protein, Nullbasic, in Human T Cells

Nullbasic is a mutant form of HIV-1 Tat that has strong ability to protect cells from HIV-1 replication by inhibiting three different steps of viral replication: reverse transcription, Rev export of viral mRNA from the nucleus to the cytoplasm and transcription of viral mRNA by RNA polymerase II. We...

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Detalhes bibliográficos
Publicado no:Virol Sin
Main Authors: Rustanti, Lina, Jin, Hongping, Li, Dongsheng, Lor, Mary, Sivakumaran, Haran, Harrich, David
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6178113/
https://ncbi.nlm.nih.gov/pubmed/29541943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12250-018-0004-7
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