Lineage relationship of CD8(+) T cell subsets is revealed by progressive changes in the epigenetic landscape

To better elucidate epigenetic mechanisms that correlate with the dynamic gene expression program observed upon T-cell differentiation, we investigated the genomic landscape of histone modifications in naive and memory CD8(+) T cells. Using a ChIP-Seq approach coupled with global gene expression pro...

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Publicado en:Cell Mol Immunol
Autores principales: Crompton, Joseph G., Narayanan, Manikandan, Cuddapah, Suresh, Roychoudhuri, Rahul, Ji, Yun, Yang, Wenjing, Patel, Shashank J., Sukumar, Madhusudhanan, Palmer, Douglas C., Peng, Weiqun, Wang, Ena, Marincola, Francesco M., Klebanoff, Christopher A., Zhao, Keji, Tsang, John S., Gattinoni, Luca, Restifo, Nicholas P.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947817/
https://ncbi.nlm.nih.gov/pubmed/25914936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2015.32
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