Lineage relationship of CD8(+) T cell subsets is revealed by progressive changes in the epigenetic landscape

To better elucidate epigenetic mechanisms that correlate with the dynamic gene expression program observed upon T-cell differentiation, we investigated the genomic landscape of histone modifications in naive and memory CD8(+) T cells. Using a ChIP-Seq approach coupled with global gene expression pro...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cell Mol Immunol
Hauptverfasser: Crompton, Joseph G., Narayanan, Manikandan, Cuddapah, Suresh, Roychoudhuri, Rahul, Ji, Yun, Yang, Wenjing, Patel, Shashank J., Sukumar, Madhusudhanan, Palmer, Douglas C., Peng, Weiqun, Wang, Ena, Marincola, Francesco M., Klebanoff, Christopher A., Zhao, Keji, Tsang, John S., Gattinoni, Luca, Restifo, Nicholas P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947817/
https://ncbi.nlm.nih.gov/pubmed/25914936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2015.32
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