Lineage relationship of CD8(+) T cell subsets is revealed by progressive changes in the epigenetic landscape

To better elucidate epigenetic mechanisms that correlate with the dynamic gene expression program observed upon T-cell differentiation, we investigated the genomic landscape of histone modifications in naive and memory CD8(+) T cells. Using a ChIP-Seq approach coupled with global gene expression pro...

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Библиографические подробности
Опубликовано в: :Cell Mol Immunol
Главные авторы: Crompton, Joseph G., Narayanan, Manikandan, Cuddapah, Suresh, Roychoudhuri, Rahul, Ji, Yun, Yang, Wenjing, Patel, Shashank J., Sukumar, Madhusudhanan, Palmer, Douglas C., Peng, Weiqun, Wang, Ena, Marincola, Francesco M., Klebanoff, Christopher A., Zhao, Keji, Tsang, John S., Gattinoni, Luca, Restifo, Nicholas P.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947817/
https://ncbi.nlm.nih.gov/pubmed/25914936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2015.32
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