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Knotting and unknotting of a protein in single molecule experiments

Spontaneous folding of a polypeptide chain into a knotted structure remains one of the most puzzling and fascinating features of protein folding. The folding of knotted proteins is on the timescale of minutes and thus hard to reproduce with atomistic simulations that have been able to reproduce feat...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Ziegler, Fabian, Lim, Nicole C. H., Mandal, Soumit Sankar, Pelz, Benjamin, Ng, Wei-Ping, Schlierf, Michael, Jackson, Sophie E., Rief, Matthias
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941514/
https://ncbi.nlm.nih.gov/pubmed/27339135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600614113
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