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Subnanometre enzyme mechanics probed by single-molecule force spectroscopy
Enzymes are molecular machines that bind substrates specifically, provide an adequate chemical environment for catalysis and exchange products rapidly, to ensure fast turnover rates. Direct information about the energetics that drive conformational changes is difficult to obtain. We used subnanometr...
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| 發表在: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4770092/ https://ncbi.nlm.nih.gov/pubmed/26906294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10848 |
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