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Subnanometre enzyme mechanics probed by single-molecule force spectroscopy

Enzymes are molecular machines that bind substrates specifically, provide an adequate chemical environment for catalysis and exchange products rapidly, to ensure fast turnover rates. Direct information about the energetics that drive conformational changes is difficult to obtain. We used subnanometr...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Pelz, Benjamin, Žoldák, Gabriel, Zeller, Fabian, Zacharias, Martin, Rief, Matthias
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770092/
https://ncbi.nlm.nih.gov/pubmed/26906294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10848
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